2-Hydroxy-4-methoxyphenylboronic acid

2-Hydroxy-4-methoxyphenylboronic acid - Names and Identifiers

Name	2-Hydroxy-4-methoxyphenylboronic acid
Synonyms	2-hydroxy-4-Methoxyphenylboronic acid 2-Hydroxy-4-methoxyphenylboronic acid Boronic acid, B-(2-hydroxy-4-methoxyphenyl)-
CAS	1068155-43-0

2-Hydroxy-4-methoxyphenylboronic acid - Physico-chemical Properties

Molecular Formula	C7H9BO4
Molar Mass	167.96
Storage Condition	2-8 ℃, stored in nitrogen

2-Hydroxy-4-methoxyphenylboronic acid - Introduction

2-Hydroxy-4-methoxybenzeneboronic acid (acid) is an organic compound with the chemical formula C7H9BO4. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystal or crystalline powder
-Melting point: 197-202°C
-Solubility: Soluble in common organic solvents, such as ethanol, dimethylformamide, etc.
-Stability: stable at room temperature, but avoid prolonged exposure to sunlight or high temperature environment

Use:
-Coordination reagent: As a reagent in the synthesis of metal complexes, it can form coordination compounds with metal ions, such as iron, zinc, etc.
-Organic synthesis: Widely used in the phenylboronic acid strategy, it can effectively synthesize organic molecules with multiple structures and functions through cross-coupling reactions similar to Suzuki-Miyaura reactions
-Pharmaceutical intermediates: As intermediates in drug development, it can be used to synthesize potential drug candidate compounds

Preparation Method:
-Usually prepared by the substitution reaction of hydroxyl and methoxy on phenylboronic acid. For example, phenylboronic acid is reacted with 2-hydroxy-4-methoxyphenyl lithium to produce 2-hydroxy-4-methoxyphenylboronic acid.

Safety Information:
-2-Hydroxy-4-methoxybenzene boronic acid is not significantly hazardous under normal conditions of use.
-But avoid its reaction with strong oxidants to prevent fire or explosion.
-And should be used correctly in accordance with laboratory safety practices, and wear appropriate personal protective equipment, such as laboratory gloves, safety glasses, etc.

Last Update：2024-04-09 02:00:41